ABSTINENCE     the psychical and physical symptoms, which appear when there is a lack of the drug.   ABSTINENCE SYNDROME     a complex of physical and psychical affection symptoms, developing due to lack of drug substance.   ADDICTION     the state of being unable to stop taking a harmful substance, especially a drug .   ALKALOIDS     substances with alkaline characteristics, containing nitrogen.   ANALGETIC     a sedative which leads to full or partial loss of the sense of pain without affecting the consci î usness.   DEPENDENCE     psychical and/or physical signs and symptoms caused by constant or periodical intake of a substance when the body and the mind get used to it. The substance becomes necessary for the functioning of the organism and the overmastering desire to intake the drug is the most typical indication of the dependence.   DEPRESSANTS     substances which suppress the central nervous system.   DEPRESSION     an emotional condition of despair and low spirit.   DOSE     the amount of drug taken once.   DRUGS     are substances which change the physical, psychical and social functions of humans.   EFFECTIVE DOSE     the dose of a given substance which causes a certain effect on 50% of people or test animals.   EUPHORIA     a pleasant sense of high spirits and well-being.   HALLUCINATIONS     something which you imagine you can see or hear, but which is not really there.   HALLUCINOGENS     substances which induce hallucinations.   MEDIATOR     a substance by means of which neurons contact with each other; all drug substances interfere in a different way in this process.   OVERDOSE     a state of temporary loss of consciousness and /or vital functions such as respiration and cardiac activity. It occurs when the intake is higher than the dose endurable for the human system.   PARANOIA     a serious mental illness that makes someone believe that they cannot trust people, or that they are trying to harm them or say bad things about them.   PHYSICAL DEPENDENCE     display of physical signs showing the need for a regular intake of the substance. When the intake is stopped specific symptoms depending on the type of the substance will occur.   PSYCHICAL DEPENDENCE     it characterizes in a n overmastering desire for new intake of the substance. When the substance lacks, general anxiety, tenseness, aggressiveness, insomnia, frequent change in mood, depression occur.   SCHIZOPHRENIA     a serious mental illness in which someone's thoughts and feelings become separated from what is really happening around them.   STIMULANTS     substances which induce psychomotor, intellectual emotional and/or senså stimulation.   SYNDROME     a combination of symptoms which have a common reason.   TOLERANCE     it is a result of a repeated use when the organism adapts to the substance and needs a larger dose in order to achieve the desired effect .   TRANQUILIZERS     sedative remedies.